理化学研究所ライフサイエンス技術基盤研究センター RIKEN Center for Life Science Technologies

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生体モデル開発ユニット 論文リスト一覧

生体モデル開発ユニット

1

A possible aid in targeted insertion of large DNA elements by CRISPR/Cas in mouse zygotes.

Nakao H, Harada T, Nakao K, Kiyonari H, Inoue K, Furuta Y, Aiba A.
Genesis., 54(2), 65-77 (2016).
2

Beneficial impact of Gpnmb and its significance as a biomarker in nonalcoholic steatohepatitis.

Katayama A, Nakatsuka A, Eguchi J, Murakami K, Teshigawara S, Kanzaki M, Nunoue T, Hida K, Wada N, Yasunaka T, Ikeda F, Takaki A, Yamamoto K, Kiyonari H, Makino H, Wada J.
Sci Rep., 5, 16920 (2015).
3

Optimizing and benchmarking de novo transcriptome sequencing: from library preparation to assembly evaluation.

Hara Y, Tatsumi K, Yoshida M, Kajikawa E, Kiyonari H, Kuraku S.
BMC Genomics., 16(1), 977 (2015).
4

The adherens junctions control susceptibility to Staphylococcus aureus α-toxin.

Popov LM, Marceau CD, Starkl PM, Lumb JH, Shah J, Guerrera D, Cooper RL, Merakou C, Bouley DM, Meng W, Kiyonari H, Takeichi M, Galli SJ, Bagnoli F, Citi S, Carette JE, Amieva MR.
Proc Natl Acad Sci U S A., 112(46), 14337-14342 (2015).
5

Calcilytic Ameliorates Abnormalities of Mutant Calcium-Sensing Receptor (CaSR) Knock-In Mice Mimicking Autosomal Dominant Hypocalcemia (ADH).

Dong B, Endo I, Ohnishi Y, Kondo T, Hasegawa T, Amizuka N, Kiyonari H, Shioi G, Abe M, Fukumoto S, Matsumoto T.
J Bone Miner Res., 30(11), 1980-1993 (2015).
6

Prolyl isomerase Pin1 negatively regulates AMP-activated protein kinase (AMPK) by associating with the CBS domain in the γ subunit.

Nakatsu Y, Iwashita M, Sakoda H, Ono H, Nagata K, Matsunaga Y, Fukushima T, Fujishiro M, Kushiyama A, Kamata H, Takahashi S, Katagiri H, Honda H, Kiyonari H, Uchida T, Asano T.
J Biol Chem., 290(40), 24255-24266 (2015).
7

Par-aPKC-dependent and -independent mechanisms cooperatively control cell polarity, Hippo signaling, and cell positioning in 16-cell stage mouse embryos.

Hirate Y, Hirahara S, Inoue K, Kiyonari H, Niwa H, Sasaki H,.
Dev Growth Differ., 57(8), 544-556 (2015).
8

Intestinal deletion of Claudin-7 enhances paracellular organic solute flux and initiates colonic inflammation in mice.

Tanaka H, Takechi M, Kiyonari H, Shioi G, Tamura A, Tsukita S.
Gut., 64(10), 1529-1538 (2015).
9

The Parkinson's Disease-Associated Protein Kinase LRRK2 Modulates Notch Signaling through the Endosomal Pathway.

Imai Y, Kobayashi Y, Inoshita T, Meng H, Arano T, Uemura K, Asano T, Yoshimi K, Zhang CL, Matsumoto G, Ohtsuka T, Kageyama R, Kiyonari H, Shioi G, Nukina N, Hattori N, Takahashi R
PLoS Genet., 11(9), e1005503 (2015).
10

Quantitative Dynamics of Chromatin Remodeling during Germ Cell Specification from Mouse Embryonic Stem Cells

Kurimoto K, Yabuta Y, Hayashi K, Ohta H, Kiyonari H, Mitani T, Moritoki Y, Kohri K, Kimura H, Yamamoto T, Katou Y, Shirahige K, Saitou M.
Cell Stem Cell, 16(5), 517-532 (2015).
11

Murine Herc6 Plays a Critical Role in Protein ISGylation In Vivo and Has an ISGylation-Independent Function in Seminal Vesicles.

Arimoto K, Hishiki T, Kiyonari H, Abe T, Cheng C, Yan M, Fan JB, Futakuchi M, Tsuda H, Murakami Y, Suzuki H, Zhang DE, Shimotohno K.
J Interferon Cytokine Res., 35(5), 351-358 (2015).
12

Nonmuscle Myosin II Regulates the Morphogenesis of Metanephric Mesenchyme-Derived Immature Nephrons.

Recuenco MC, Ohmori T, Tanigawa S, Taguchi A, Fujimura S, Conti MA, Wei Q, Kiyonari H, Abe T, Adelstein RS, Nishinakamura R.
J Am Soc Nephrol., 26(05), 1081-1091 (2015).
13

Fatty acid remodeling by LPCAT3 enriches arachidonate in phospholipid membranes and regulates triglyceride transport.

Hashidate-Yoshida T, Harayama T, Hishikawa D, Morimoto R, Hamano F, Tokuoka SM, Eto M, Tamura-Nakano M, Yanobu-Takanashi R, Mukumoto Y, Kiyonari H, Okamura T, Kita Y, Shindou H, Shimizu T.
Elife., 4, (2015).
14

IFT46 plays an essential role in cilia development.

Lee MS, Hwang KS, Oh HW, Ji-Ae K, Kim HT, Cho HS, Lee JJ, Yeong Ko J, Choi JH, Jeong YM, You KH, Kim J, Park DS, Nam KH, Aizawa S, Kiyonari H, Shioi G, Park JH, Zhou W, Kim NS, Kim CH.
Dev Biol., 400(2), 248-257 (2015).
15

Atrial natriuretic peptide prevents cancer metastasis through vascular endothelial cells.

Nojiri T, Hosoda H, Tokudome T, Miura K, Ishikane S, Otani K, Kishimoto I, Shintani Y, Inoue M, Kimura T, Sawabata N, Minami M, Nakagiri T, Funaki S, Takeuchi Y, Maeda H, Kidoya H, Kiyonari H, Shioi G, Arai Y, Hasegawa T, Takakura N, Hori M, Ohno Y, Miyazato M, Mochizuki N, Okumura M, Kangawa K.
Proc Natl Acad Sci U S A, 112(13), 4086-4091 (2015).
16

Singular localization of sodium channel β4 subunit in unmyelinated fibres and its role in the striatum.

Miyazaki H, Oyama F, Inoue R, Aosaki T, Abe T, Kiyonari H, Kino Y, Kurosawa M, Shimizu J, Ogiwara I, Yamakawa K, Koshimizu Y, Fujiyama F, Kaneko T, Shimizu H, Nagatomo K, Yamada K, Shimogori T, Hattori N, Miura M, Nukina N.
Nat Commun,(5), 5525 (2014).
17

Protocadherin-17 Mediates Collective Axon Extension by Recruiting Actin Regulator Complexes to Interaxonal Contacts

Hayashi S, Inoue Y, Kiyonari H, Abe T, Misaki K, Moriguchi H, Tanaka Y, Takeichi M
Dev Cell, 30(6), 673-687 (2014).
18

Conserved Neutralizing Epitope at Globular Head of Hemagglutinin in H3N2 Influenza Viruses

Iba Y, Fujii Y, Ohshima N, Sumida T, Kubota-Koketsu R, Ikeda M, Wakiyama M, Shirouzu M, Okada J, Okuno Y, Kurosawa Y, Yokoyama S.
J Virol, 88(13), 7130-7144 (2014).
19

Epac1-dependent phospholamban phosphorylation mediates the cardiac response to stresses.

Okumura S, Fujita T, Cai W, Jin M, Namekata I, Mototani Y, Jin H, Ohnuki Y, Tsuneoka Y, Kurotani R, Suita K, Kawakami Y, Hamaguchi S, Abe T, Kiyonari H, Tsunematsu T, Bai Y, Suzuki S, Hidaka Y, Umemura M, Ichikawa Y, Yokoyama U, Sato M, Ishikawa F, Izumi-Nakaseko H, Adachi-Akahane S, Tanaka H, Ishikawa Y.
J Clin Invest., 124(6), 2785-2801 (2014).
20

Whole-brain imaging with single-cell resolution using chemical cocktails and computational analysis.

Susaki EA, Tainaka K, Perrin D, Kishino F, Tawara T, Watanabe TM, Yokoyama C, Onoe H, Eguchi M, Yamaguchi S, Abe T, Kiyonari H, Shimizu Y, Miyawaki A, Yokota H, Ueda HR.
Cell, 157(3), 726-739 (2014).