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Cellular Dynamics Analysis Unit Publications

Cellular Dynamics Analysis Unit


Three-dimensional tracking of plus-tips by lattice light-sheet microscopy permits the quantification of microtubule growth trajectories within the mitotic apparatus

Yamashita N, Morita M, Legant WR, Chen BC, Betzig E, Yokota H, Mimori-Kiyosue Y
J Biomed Opt., 20(10), 101206 (2015).

[11C]Cetrozole: an Improved C-[11C]Methylated PET Probe for Aromatase Imaging in the Brain.

Takahashi K, Hosoya T, Onoe K, Doi H, Nagata H, Hiramatsu T, Li XL, Watanabe Y, Wada Y, Takashima T, Suzuki M, Onoe H, Watanabe Y.
J Nucl Med, 55(5), 852-857 (2014).

CFEOM1-associated kinesin KIF21A is a cortical microtubule growth inhibitor.

van der Vaart B, van Riel WE, Doodhi H, Kevenaar JT, Katrukha EA, Gumy L, Bouchet BP, Grigoriev I, Spangler SA, Yu KL, Wulf PS, Wu J, Lansbergen G, van Battum EY, Pasterkamp RJ, Mimori-Kiyosue Y, Demmers J, Olieric N, Maly IV, Hoogenraad CC, Akhmanova A.
Dev Cell., 27(2), 145-160 (2013).

The action site of the synthetic kainoid (2S,3R,4R)-3-carboxymethyl-4-(4-methylphenylthio) pyrrolidine-2-carboxylic acid (PSPA-4), an analogue of Japanese mushroom poison acromelic acid, for allodynia (tactile pain)

Miyazaki S, Minami T, Mizuma H, Kanazawa M, Doi H, Matsumura S, Lu JS, Onoe H, Furuta K, Suzuki M, Ito S.
Eur J Pharmacol, 710(1-3), 120-127 (2013).

Improving spinning disk confocal microscopy by preventing pinhole cross-talk for intravital imaging.

Shimozawa T, Yamagata K, Kondo T, Hayashi S, Shitamukai A, Konno D, Matsuzaki F, Takayama J, Onami S, Nakayama H, Kosugi Y, Watanabe TM, Fujita K, Mimori-Kiyosue Y.
Proc Natl Acad Sci U S A, 110(9), 3399-3404 (2013).

Dynamic microtubules at the vegetal cortex predict the embryonic axis in zebrafish.

Tran LD, Hino H, Quach H, Lim S, Shindo A, Mimori-Kiyosue Y, Mione M, Ueno N, Winkler C, Hibi M, Sampath K.
Development., 139(19), 3644-3652 (2012).

Shaping microtubules into diverse patterns: molecular connections for setting up both ends.

Mimori-Kiyosue Y.
Cytoskeleton (Hoboken), 68(11), 603-618 (2011).

Regulation of interkinetic nuclear migration by cell cycle-coupled active and passive mechanisms in the developing brain.

Kosodo Y, Suetsugu T, Suda M, Mimori-Kiyosue Y, Toida K, Baba SA, Kimura A, Matsuzaki F.
EMBO J., 30(9), 1690-1704 (2011).

Dissecting cell signaling pathways with genetically encoded 3-iodo-L-tyrosine

Hayashi A, Hino N, Kobayashi T, Arai R, Shirouzu M, Yokoyama S, Sakamoto K.
Chembiochem, 12(3), 387-389 (2011).

Structural basis of the recognition of the SAMP motif of adenomatous polyposis coli by the Src-homology 3 domain.

Kaieda S, Matsui C, Mimori-Kiyosue Y, Ikegami T.
Biochemistry., 49(25), 5143-5153 (2010).

Laminin-based cell adhesion anchors microtubule plus ends to the epithelial cell basal cortex through LL5α/β

Hotta A, Kawakatsu T, Nakatani T, Sato T, Matsui C, Sukezane T, Akagi T, Hamaji T, Grigoriev I, Akhmanova A, Takai Y, Mimori-Kiyosue Y
J Cell Biol, 189(5), 901-917 (2010).

The PX-RICS-14-3-3zeta/theta complex couples N-cadherin-beta-catenin with dynein-dynactin to mediate its export from the endoplasmic reticulum.

Nakamura T, Hayashi T, Mimori-Kiyosue Y, Sakaue F, Matsuura K, Iemura S, Natsume T, Akiyama T.
J Biol Chem., 285(21), 16145-16154 (2010).

An essential role of the aPKC-Aurora A-NDEL1 pathway in neurite elongation by modulation of microtubule dynamics.

Mori D, Yamada M, Mimori-Kiyosue Y, Shirai Y, Suzuki A, Ohno S, Saya H, Wynshaw-Boris A, Hirotsune S.
Nat Cell Biol., 11(9), 1057-1068 (2009).

Identification of a link between the SAMP repeats of adenomatous polyposis coli tumor suppressor and the Src homology 3 domain of DDEF.

Matsui C, Kaieda S, Ikegami T, Mimori-Kiyosue Y.
J Biol Chem, 283(47), 33006-33020 (2008).

LIS1 and NDEL1 coordinate the plus-end-directed transport of cytoplasmic dynein.

Yamada M, Toba S, Yoshida Y, Haratani K, Mori D, Yano Y, Mimori-Kiyosue Y, Nakamura T, Itoh K, Fushiki S, Setou M, Wynshaw-Boris A, Torisawa T, Toyoshima YY, Hirotsune S.
EMBO J., 27(19), 2471-2483 (2008).

Structural basis for the recognition between the regulatory particles Nas6 and Rpt3 of the yeast 26S proteasome.

Nakamura Y, Umehara T, Tanaka A, Horikoshi M, Padmanabhan B, Yokoyama S.
Biochem Biophys Res Commun, 359(3), 503-509 (2007).

Mammalian CLASPs are required for mitotic spindle organization and kinetochore alignment.

Mimori-Kiyosue Y, Grigoriev I, Sasaki H, Matsui C, Akhmanova A, Tsukita S, Vorobjev I.
Genes Cells., 11(8), 845-857 (2006).

CLASPs attach microtubule plus ends to the cell cortex through a complex with LL5beta.

Lansbergen G, Grigoriev I, Mimori-Kiyosue Y, Ohtsuka T, Higa S, Kitajima I, Demmers J, Galjart N, Houtsmuller AB, Grosveld F, Akhmanova A
Dev Cell., 11(1), 21-32 (2006).

CLASP1 and CLASP2 bind to EB1 and regulate microtubule plus-end dynamics at the cell cortex.

Mimori-Kiyosue Y, Grigoriev I, Lansbergen G, Sasaki H, Matsui C, Severin F, Galjart N, Grosveld F, Vorobjev I, Tsukita S, Akhmanova A.
J Cell Biol, 168(1), 141-153 (2005).

Search-and-capture of microtubules through plus-end-binding proteins (+TIPs).

Mimori-Kiyosue Y, Tsukita S.
J Biochem, 134(3), 321-326 (2003).

Dynamic behavior of paired claudin strands within apposing plasma membranes.

Sasaki H, Matsui C, Furuse K, Mimori-Kiyosue Y, Furuse M, Tsukita S.
Proc Natl Acad Sci U S A., 100(7), 3971-3976 (2003).

Where is APC going?

Mimori-Kiyosue Y, Tsukita S.
J Cell Biol, 154(6), 1105-1109 (2001).

Rapid functional analysis of protein-protein interactions by fluorescent C-terminal labeling and single-molecule imaging.

Yamaguchi J, Nemoto N, Sasaki T, Tokumasu A, Mimori-Kiyosue Y, Yagi T, Funatsu T.
FEBS Lett., 502(3), 79-83 (2001).

The dynamic behavior of the APC-binding protein EB1 on the distal ends of microtubules.

Mimori-Kiyosue Y, Shiina N, Tsukita S.
Curr Biol, 10(14), 865-868 (2000).

Role of the outermost subdomain of Salmonella flagellin in the filament structure revealed by electron cryomicroscopy.

Mimori-Kiyosue Y, Yamashita I, Fujiyoshi Y, Yamaguchi S, Namba K.
J Mol Biol., 284(2), 521-530 (1998).

Direct interaction of flagellin termini essential for polymorphic ability of flagellar filament.

Mimori-Kiyosue Y, Vonderviszt F, Yamashita I, Fujiyoshi Y, Namba K.
Proc Natl Acad Sci U S A, 93(26), 15108-15113 (1996).

Radial mass analysis of the flagellar filament of Salmonella: implications for the subunit folding.

Yamashita I, Vonderviszt F, Mimori Y, Suzuki H, Oosawa K, Namba K.
J Mol Biol, 253(4), 547-558 (1995).

The structure of the R-type straight flagellar filament of Salmonella at 9 A resolution by electron cryomicroscopy.

Mimori Y, Yamashita I, Murata K, Fujiyoshi Y, Yonekura K, Toyoshima C, Namba K.
J Mol Biol., 249(1), 69-87 (1995).

Extrusion of rotating microtubules on the dynein-track from a microtubule-dynein gamma-complex.

Mimori Y, Miki-Noumura T.
Cell Motil Cytoskeleton., 30(1), 17-25 (1995).

ATP-induced sliding of microtubules on tracks of 22S dynein molecules aligned with the same polarity.

Mimori Y, Miki-Noumura T.
Cell Motil Cytoskeleton, 27(2), 180-191 (1994).

CLST was reorganized into three centers according to the RIKEN 4th Medium-Term Plan from April 1, 2018. For the latest information of Cellular Dynamics Analysis Unit, please visit the following websites.

> The webpage of Laboratory for Molecular and Cellular Dynamics, Center for Biosystems Dynamics Research [http://www.bdr.riken.jp/en/research/labs/kiyosue-y/index.html]